RHOD antibody (N-Term)

Catalog No. ABIN2775403

Product Details anti-RHOD Antibody

Target: RHOD (Ras Homolog Family Member D (RHOD))

Binding Specificity: N-Term

Reactivity: Human, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHOD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TAAQAAGEEA PPGVRSVKVV LVGDGGCGKT SLLMVFADGA FPESYTPTVF

Predicted Reactivity: Guinea Pig: 79%, Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against RHOD. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RHOD

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 210 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-RHOD antibody (ABIN2775403)

Tong, Chugha, Hota, Alviani, Li, Tempel, Shen, Park, Buck: "Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain." in: The Journal of biological chemistry, Vol. 282, Issue 51, pp. 37215-24, (2007) (PubMed).

Target Details for RHOD

Target: RHOD (Ras Homolog Family Member D (RHOD))

Alternative Name: RHOD (RHOD Products)

Synonyms: ARHD antibody, RHOHP1 antibody, RHOM antibody, Rho antibody, AI326383 antibody, Arhd antibody, RhoHP1 antibody, RhoM antibody, ras homolog family member D antibody, RHOD antibody, Rhod antibody

Background: Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. RHOD binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ARHD, RHOHP1, RHOM, Rho
Protein Interaction Partner: ADRB2, IHH, ADCK5, UBC, PLXNA1, SMURF2, BMPR1B, SMAD2, SMAD4, DIAPH2, TGFBR1, HRAS, ACVR1, CNKSR1, ARHGAP29,
Protein Size: 210

Molecular Weight: 23 kDa

Gene ID: 29984

NCBI Accession: NM_014578, NP_055393

UniProt: O00212