TMEM2 antibody (Middle Region)

Catalog No. ABIN2775385

Product Details anti-TMEM2 Antibody

Target: TMEM2 (Transmembrane Protein 2 (TMEM2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MLTGLCQGCG TRQVVFTSDP HKSYLPVQFQ SPDKAETQRG DPSVISVNGT

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TMEM2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TMEM2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1383 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TMEM2 antibody (ABIN2775385)

Zhu, Xie, Li, Huang, Zhao, Hu, Wang, Gu, Gao, Peng: "TMEM2 inhibits hepatitis B virus infection in HepG2 and HepG2.2.15 cells by activating the JAK-STAT signaling pathway." in: Cell death & disease, Vol. 7, Issue 6, pp. e2239, (2016) (PubMed).

Target Details for TMEM2

Target: TMEM2 (Transmembrane Protein 2 (TMEM2))

Alternative Name: TMEM2 (TMEM2 Products)

Synonyms: 3110012M15Rik antibody, mKIAA1412 antibody, transmembrane protein 2 antibody, tmem2 antibody, TMEM2 antibody, Tmem2 antibody

Background: The function of this protein remains unknown.
Alias Symbols: -
Protein Interaction Partner: FBXO6, UBC, ELAVL1,
Protein Size: 1383

Molecular Weight: 154 kDa

Gene ID: 23670

NCBI Accession: NM_013390, NP_037522

UniProt: Q9UHN6