Peroxidasin antibody (N-Term)

Catalog No. ABIN2775373

Product Details anti-Peroxidasin Antibody

Target: Peroxidasin (PXDN) (Peroxidasin Homolog (PXDN))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Guinea Pig, Horse, Dog, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxidasin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NLKYLYLYKN EIQSIDRQAF KGLASLEQLY LHFNQIETLD PDSFQHLPKL

Predicted Reactivity: Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PXDN. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PXDN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Peroxidasin

Target: Peroxidasin (PXDN) (Peroxidasin Homolog (PXDN))

Alternative Name: PXDN (PXDN Products)

Synonyms: D2S448 antibody, D2S448E antibody, MG50 antibody, PRG2 antibody, PXN antibody, VPO antibody, 2310075M15Rik antibody, C85409 antibody, E330004E07 antibody, VPO1 antibody, mKIAA0230 antibody, peroxidasin antibody, PXDN antibody, Pxdn antibody

Background: Drosophila peroxidasin is an extracellular matrix-associated peroxidase (Horikoshi et al., 1999 [PubMed 10441517]). It is expressed exclusively in hemocytes derived from head mesoderm at a very early stage of differentiation. Peroxidasin exists as a homotrimer with a unique hybrid structure that combines an enzymatically functional peroxidase domain with motifs that are typically found in extracellular matrix-associated proteins. It is a secreted protein that contains a secretory recognition sequence at its N terminus. Peroxidasin catalyzes hydrogen peroxide-driven radioiodination, oxidations, and the formation of dityrosine in vitro. It is also thought to function in extracellular matrix consolidation, phagocytosis, and defense.
Protein Interaction Partner: HECW2, BNIPL, FBXO6, TRAF4,
Protein Size: 727

Molecular Weight: 79 kDa

Gene ID: 7837