ACOT2 antibody (Middle Region)

Catalog No. ABIN2775350

Product Details anti-ACOT2 Antibody

Target: ACOT2 (Acyl-CoA Thioesterase 2 (ACOT2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACOT2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SPLEGPDQKS FIPVERAEST FLFLVGQDDH NWKSEFYANE ACKRLQAHGR

Predicted Reactivity: Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against ACOT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACOT2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 483 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ACOT2 antibody (ABIN2775350)

Hwang, Dornbos, Steidemann, Dunivin, Rizzo, LaPres: "Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome." in: Toxicology and applied pharmacology, (2016) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for ACOT2

Target: ACOT2 (Acyl-CoA Thioesterase 2 (ACOT2))

Alternative Name: ACOT2 (ACOT2 Products)

Synonyms: MGC83099 antibody, CTE-IA antibody, CTE1A antibody, MTE1 antibody, PTE2 antibody, PTE2A antibody, ZAP128 antibody, AA571646 antibody, MTE-I antibody, Mte1 antibody, acyl-CoA thioesterase 2 S homeolog antibody, acyl-CoA thioesterase 2 antibody, acyl-coenzyme A thioesterase 1 antibody, acot2.S antibody, ACOT2 antibody, LOC490770 antibody, acot2 antibody, LOC100344509 antibody, Acot2 antibody

Background: Acyl-CoA thioesterases, such as ACOT2, are a group of enzymes that hydrolyze CoA esters, such as acyl-CoAs, bile CoAs, and CoA esters of prostaglandins, to the corresponding free acid and CoA.Acyl-CoA thioesterases, such as ACOT2, are a group of enzymes that hydrolyze CoA esters, such as acyl-CoAs, bile CoAs, and CoA esters of prostaglandins, to the corresponding free acid and CoA (Hunt et al., 2005 [PubMed 16103133]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-7 CR610624.1 1-7 8-1155 BC006335.2 1-1148 1156-1767 L40401.1 468-1079
Alias Symbols: Mte1, PTE2, ZAP128, MTE1, CTE1A, PTE2A
Protein Interaction Partner: UBC, PEX5, ZNF277,
Protein Size: 483

Molecular Weight: 53 kDa

Gene ID: 10965

NCBI Accession: NM_006821, NP_006812

UniProt: P49753

Pathways: Monocarboxylic Acid Catabolic Process