PPP1R1A antibody (N-Term)

Catalog No. ABIN2775347

Product Details anti-PPP1R1A Antibody

Target: PPP1R1A (Protein Phosphatase Inhibitor 1 (PPP1R1A))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R1A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FTVPLLEPHL DPEAAEQIRR RRPTPATLVL TSDQSSPEID EDRIPNSLLK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Ppp1r1a. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 171 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP1R1A

Target: PPP1R1A (Protein Phosphatase Inhibitor 1 (PPP1R1A))

Alternative Name: Ppp1r1a (PPP1R1A Products)

Synonyms: I1 antibody, IPP1 antibody, 0610038N18Rik antibody, I-1 antibody, pil antibody, IPP-1 antibody, protein phosphatase 1 regulatory inhibitor subunit 1A antibody, protein phosphatase 1, regulatory (inhibitor) subunit 1A antibody, protein phosphatase 1 regulatory inhibitor subunit 1A L homeolog antibody, PPP1R1A antibody, Ppp1r1a antibody, ppp1r1a.L antibody

Background: Ppp1r1a is an inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
Alias Symbols: 0610038N18Rik, I-1
Protein Size: 171

Molecular Weight: 19 kDa

Gene ID: 58200

NCBI Accession: NM_021391, NP_067366

UniProt: Q9ERT9

Pathways: Cellular Glucan Metabolic Process