MYH1 antibody (N-Term)

Catalog No. ABIN2775330

Product Details anti-MYH1 Antibody

Target: MYH1 (Myosin Heavy Chain 1, Skeletal Muscle, Adult (MYH1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Sheep, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYH1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KTSVFVVDPK ESFVKATVQS REGGKVTAKT EAGATVTVKD DQVFPMNPPK

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against MYH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MYH1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1939 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MYH1 antibody (ABIN2775330)

Rouillon, Poupiot, Zocevic, Amor, Léger, Garcia, Camadro, Wong, Pinilla, Cosette, Coenen-Stass, Mcclorey, Roberts, Wood, Servais, Udd, Voit, Richard, Svinartchouk: "Serum proteomic profiling reveals fragments of MYOM3 as potential biomarkers for monitoring the outcome of therapeutic interventions in muscular dystrophies." in: Human molecular genetics, Vol. 24, Issue 17, pp. 4916-32, (2016) (PubMed).

Avezzù, Agostini, Pucciarelli, Lise, Urso, Mammi, Maretto, Enzo, Pastrello, Lise, Nitti, Viel: "The role of MYH gene in genetic predisposition to colorectal cancer: another piece of the puzzle." in: Cancer letters, Vol. 268, Issue 2, pp. 308-13, (2008) (PubMed).

Target Details for MYH1

Target: MYH1 (Myosin Heavy Chain 1, Skeletal Muscle, Adult (MYH1))

Alternative Name: MYH1 (MYH1 Products)

Synonyms: MYH1 antibody, MYH6 antibody, adult antibody, myosin antibody, A530084A17Rik antibody, IId antibody, IId/x antibody, MHC-2X/D antibody, MHC2X/D antibody, MYHC-IIX antibody, MdMs antibody, MyHC-IId/x antibody, MyHC-IIx/d antibody, Myhs-f antibody, Myhs-f2 antibody, Myhsf2 antibody, MYHC antibody, MYHSA1 antibody, MYHa antibody, MyHC-2X/D antibody, MyHC-2x antibody, MYHC-2X antibody, MYHC-2d antibody, myosin, heavy chain 1E, skeletal muscle antibody, myosin, heavy polypeptide 1, skeletal muscle, adult antibody, myosin heavy chain 1 antibody, myosin, heavy chain 1, skeletal muscle, adult antibody, myosin-8 antibody, myosin-1 antibody, myosin type I antibody, MYH1E antibody, Myh1 antibody, MYH1 antibody, LOC100303760 antibody, LOC100726730 antibody, myo1 antibody

Background: Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin hea
Alias Symbols: MGC133384, MYHSA1, MYHa, MyHC-2X/D, MyHC-2x
Protein Interaction Partner: KRT13, WWOX, PIK3C3, ARRB1, UBC, STAU1,
Protein Size: 1939

Molecular Weight: 223 kDa

Gene ID: 4619

NCBI Accession: NM_005963, NP_005954

UniProt: P12882