MAK antibody (C-Term)

Catalog No. ABIN2775329

Product Details anti-MAK Antibody

Target: MAK (Male Germ Cell-Associated Kinase (MAK))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: WNTKTGRGQF SGRTYNPTAK NLNIVNRAQP IPSVHGRTDW VAKYGGHR

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MAK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MAK

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 623 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAK

Target: MAK (Male Germ Cell-Associated Kinase (MAK))

Alternative Name: MAK (MAK Products)

Synonyms: RP62 antibody, dJ417M14.2 antibody, A930010O05Rik antibody, Ick antibody, fj04c02 antibody, wu:fj04c02 antibody, zgc:56603 antibody, rp62 antibody, xmak antibody, MGC82717 antibody, MGC146434 antibody, male germ cell associated kinase antibody, male germ cell-associated kinase antibody, male germ cell associated kinase L homeolog antibody, MAK antibody, Mak antibody, mak antibody, mak.L antibody

Background: MAK is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized.The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized.
Alias Symbols: dJ417M14.2, RP62
Protein Interaction Partner: MAK, SLAMF7, SERINC1, ANAPC11, SND1, PPP2CB, NDUFB7, APP, FZR1, CDK20,
Protein Size: 623

Molecular Weight: 70 kDa

Gene ID: 4117

NCBI Accession: NM_005906, NP_005897

UniProt: P20794