KRT16 antibody (Middle Region)

Catalog No. ABIN2775314

Product Details anti-KRT16 Antibody

Target: KRT16 (Keratin 16 (KRT16))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Guinea Pig, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRT16 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IAATIENAQP ILQIDNARLA ADDFRTKYEH ELALRQTVEA DVNGLRRVLD

Predicted Reactivity: Cow: 92%, Dog: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against KRT16. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KRT16

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 473 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-KRT16 antibody (ABIN2775314)

Furukawa, Abe, Wang, Oki, Uda, Tsuneda, Ito: "Fluorogenic probe triggered by reduction for nucleic acids sensing." in: Nucleic acids symposium series (2004), Issue 52, pp. 353-4, (2008) (PubMed).

Target Details for KRT16

Target: KRT16 (Keratin 16 (KRT16))

Alternative Name: KRT16 (KRT16 Products)

Background: KRT16 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles.The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CK16, K16, K1CP, KRT16A, NEPPK, FNEPPK
Protein Interaction Partner: UBC, Cep290, Nphp1, Invs, IQCB1, ITGA4, FN1, APOA1, ALB, EIF4A3, HNRNPM, UBASH3B, SHC1, PIK3R2, INPPL1, GRB2, EPS15, CRK, AP2M1, CBL, CAND1, COPS5, CUL1, CUL2, CUL3, CUL4B, NEDD8, BANF1, TCHP,
Protein Size: 473

Molecular Weight: 51 kDa

Gene ID: 3868

NCBI Accession: NM_005557, NP_005548

UniProt: P08779