CES2 antibody (C-Term)

Catalog No. ABIN2775271

Product Details anti-CES2 Antibody

Target: CES2 (Carboxylesterase 2 (CES2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CES2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: HWPLFDQEEQ YLQLNLQPAV GRALKAHRLQ FWKKALPQKI QELEEPEERH

Predicted Reactivity: Dog: 83%, Guinea Pig: 83%, Human: 100%, Mouse: 83%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against CES2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CES2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 623 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CES2 antibody (ABIN2775271)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Target Details for CES2

Target: CES2 (Carboxylesterase 2 (CES2))

Alternative Name: CES2 (CES2 Products)

Synonyms: CE-2 antibody, CES2A1 antibody, PCE-2 antibody, iCE antibody, Ces2 antibody, im:6908784 antibody, si:dkey-38l12.2 antibody, zgc:153863 antibody, ce-2 antibody, ces2a1 antibody, pce-2 antibody, carboxylesterase 2 antibody, liver carboxylesterase 2 antibody, cocaine esterase antibody, carboxylesterase 2 (intestine, liver) antibody, CES2 antibody, Ces2 antibody, LOC100343300 antibody, LOC100734360 antibody, ces2 antibody

Background: Carboxylesterase 2 is a member of a large multigene family. The enzymes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined, however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system.Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined, however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: CE-2, iCE, PCE-2, CES2A1
Protein Size: 623

Molecular Weight: 69 kDa

Gene ID: 8824

NCBI Accession: NM_003869, NP_003860

UniProt: O00748