TDRD9 antibody (C-Term)

Catalog No. ABIN2775265

Product Details anti-TDRD9 Antibody

Target: TDRD9 (Tudor Domain Containing 9 (TDRD9))

Binding Specificity: C-Term

Reactivity: Human, Rabbit, Horse, Cow, Dog, Guinea Pig, Mouse, Rat, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TDRD9 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PHPDLVCLAP FADFDKQRYF RAQVLYVSGN SAEVFFVDYG NKSHVDLHLL

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 89%

Characteristics: This is a rabbit polyclonal antibody against TDRD9. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TDRD9

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TDRD9

Target: TDRD9 (Tudor Domain Containing 9 (TDRD9))

Alternative Name: TDRD9 (TDRD9 Products)

Synonyms: MGC146806 antibody, C14orf75 antibody, HIG-1 antibody, NET54 antibody, 4930441E05Rik antibody, si:dkey-15f17.9 antibody, tdrd9l antibody, tudor domain containing 9 antibody, TDRD9 antibody, tdrd9 antibody, Tdrd9 antibody

Background: TDRD9 is a probable ATP-binding RNA helicase which plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. TDRD9 acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with PIWIL4 and the piP-bodies suggests a participation in the secondary piRNAs metabolic process.
Alias Symbols: C14orf75, HIG-1, NET54
Protein Interaction Partner: PPP2R1A, UBC,
Protein Size: 1382

Molecular Weight: 152 kDa

Gene ID: 122402

NCBI Accession: NM_153046, NP_694591

UniProt: Q8NDG6