DDX58 antibody (Middle Region)
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- Target See all DDX58 Antibodies
- DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DDX58 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- EECHYTVLGD AFKECFVSRP HPKPKQFSSF EKRAKIFCAR QNCSHDWGIH
- Predicted Reactivity
- Horse: 79%, Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against DDX58. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human DDX58
- Top Product
- Discover our top product DDX58 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 925 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))
- Alternative Name
- DDX58 (DDX58 Products)
- Background
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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein
Alias Symbols: DKFZp434J1111, DKFZp686N19181, FLJ13599, RIG-I
Protein Interaction Partner: MAVS, TRIM25, RNF135, TRIM26, UBC, MEX3C, USP21, USP3, TBK1, IKBKE, IKBKG, Casp12, NLRC5, DDX58, USP4, MBP, IRF3, SRC, TSPAN6, TRIM32, ISG15, PRKCG, PRKCB, PRKCA, WRNIP1, RNF31, RAI14, RBCK1, PRKRIR, UBE2D3, UBE2D2, UBE2D1, UBE2K, CYLD,
Protein Size: 925 - Molecular Weight
- 106 kDa
- Gene ID
- 23586
- NCBI Accession
- NM_014314, NP_055129
- UniProt
- O95786
- Pathways
- Activation of Innate immune Response, Hepatitis C
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