DDX42 antibody (N-Term)

Catalog No. ABIN2775212

Product Details anti-DDX42 Antibody

Target: DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX42 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PLEAFMAEVE DQAARDMKRL EEKDKERKNV KGIRDDIEEE DDQEAYFRYM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DDX42. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DDX42

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 938 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DDX42

Target: DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))

Alternative Name: DDX42 (DDX42 Products)

Synonyms: im:7148194 antibody, si:dkey-15n1.10 antibody, zgc:111815 antibody, DDX42P antibody, RHELP antibody, RNAHP antibody, SF3b125 antibody, 1810047H21Rik antibody, AW319508 antibody, AW556242 antibody, B430002H05Rik antibody, DEAD (Asp-Glu-Ala-Asp) box helicase 42 antibody, DEAD-box helicase 42 antibody, DEAD-box helicase 42 L homeolog antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 antibody, ddx42 antibody, DDX42 antibody, Ddx42 antibody, ddx42.L antibody

Background: DDX42 is a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX42 is a ATP-dependent RNA helicase. DDX42 binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. It also mediates RNA duplex formation thereby displacing the single-strand RNA binding protein.This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: FLJ43179, RHELP, RNAHP, SF3b125
Protein Interaction Partner: FUS, UBC, SUMO1, EED, SHFM1, FBXO25, LMNA, PRPF19, U2SURP, SF3A1, SF3B4, SNRPC, ITGA4, DHX15, PIN4, KAL1, EPRS, APP, PHF20, NOSIP, RPL36, FOXJ3, TCERG1, SYNCRIP, RPS6KA4, SUMO3, ISG15, SIRT7, SF3A2, MEPCE, RUVBL2, RUVBL1, RECQL5, SF3B1,
Protein Size: 938

Molecular Weight: 103 kDa

Gene ID: 11325

NCBI Accession: NM_007372, NP_031398

UniProt: Q86XP3