DDX39 antibody (N-Term)

Catalog No. ABIN2775205

Product Details anti-DDX39 Antibody

Target: DDX39 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39A (DDX39))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX39 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MAEQDVENDL LDYDEEEEPQ APQESTPAPP KKDIKGSYVS IHSSGFRDFL

Predicted Reactivity: Cow: 77%, Dog: 79%, Guinea Pig: 79%, Human: 100%, Mouse: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against DDX39. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DDX39

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 427 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-DDX39 antibody (ABIN2775205)

Majerciak, Deng, Zheng: "Requirement of UAP56, URH49, RBM15, and OTT3 in the expression of Kaposi sarcoma-associated herpesvirus ORF57." in: Virology, Vol. 407, Issue 2, pp. 206-12, (2010) (PubMed).

Target Details for DDX39

Target: DDX39 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39A (DDX39))

Alternative Name: DDX39 (DDX39 Products)

Synonyms: 2610307C23Rik antibody, BAT1 antibody, DDXL antibody, Ddx39a antibody, URH49 antibody, BAT1L antibody, DDX39 antibody, Ddx39 antibody, Ddxl antibody, ddx39a antibody, wu:fc87b12 antibody, zgc:55881 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 antibody, DExD-box helicase 39A antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa antibody, Ddx39 antibody, DDX39A antibody, Ddx39a antibody, ddx39aa antibody

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX39 encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants encoding different isoforms.
Alias Symbols: BAT1, DDXL, BAT1L, DDX39, URH49
Protein Interaction Partner: SAT1, SARNP, DDX39A, UBC, MDM2, EED, C12orf10, NAGK, SUGT1, AHSA1, SORD, SMS, GSR, PARP1, SRPK2, SOX2, FBXO6, UBD, TERF2IP, TERF2, TERF1, SUMO1, SUMO2, PTK2, Bud13, AI837181, Erh, UBA5, GBAS, ALYREF, BABAM1, EXOSC9, HIPK2, CCL14, DDX39B,
Protein Size: 427

Molecular Weight: 47 kDa

Gene ID: 10212

NCBI Accession: NM_005804, NP_005795

UniProt: O00148