DHX16 antibody (N-Term)

Catalog No. ABIN2775187

Product Details anti-DHX16 Antibody

Target: DHX16 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 16 (DHX16))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Cow, Horse, Rat, Goat, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHX16 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RREYLAKRER EKLEDLEAEL ADEEFLFGDV ELSRHERQEL KYKRRVRDLA

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against DHX16. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 981 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DHX16

Target: DHX16 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 16 (DHX16))

Alternative Name: DHX16 (DHX16 Products)

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DBP2, DDX16, PRO2014, PRP8, PRPF2, Prp2
Protein Interaction Partner: NUDCD1, UBC, GPKOW, SF3B2, DHX38, DGCR14, CSNK2A1, XAB2, HELQ, PYROXD1, NAA40, LSM2, MIF4GD, GON4L, WDR44, EHD2, LSM5, LSM6, GCC2, TCEA2, MTR, GSPT1, GABPB1, APP, COIL, SNRNP27, SNRNP40, SIRT7, MEGF10, Bud13, TADA2A, SRRM2, SRRM1,
Protein Size: 981

Molecular Weight: 107 kDa

Gene ID: 8449

NCBI Accession: NM_001164239, NP_001157711

UniProt: B4DZ28