AKAP10 antibody (Middle Region)

Catalog No. ABIN2775175

Product Details anti-AKAP10 Antibody

Target: AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Horse, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKAP10 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ESLYQRTYAG KMTFGRVSDL GQFIRESEPE PDVRKSKGSM FSQAMKKWVQ

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against AKAP10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AKAP10

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 662 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AKAP10

Target: AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))

Alternative Name: AKAP10 (AKAP10 Products)

Synonyms: MGC84612 antibody, AKAP10 antibody, fc10g11 antibody, wu:fc10g11 antibody, si:dkey-197m14.4 antibody, AKAP-10 antibody, D-AKAP-2 antibody, D-AKAP2 antibody, PRKA10 antibody, 1500031L16Rik antibody, B130049N18Rik antibody, D-akap2 antibody, Akap10 antibody, A-kinase anchoring protein 10 antibody, A-kinase anchoring protein 10 L homeolog antibody, A kinase (PRKA) anchor protein 10 antibody, AKAP10 antibody, akap10.L antibody, akap10 antibody, Akap10 antibody

Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA, therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.
Alias Symbols: D-AKAP2, MGC9414, PRKA10
Protein Interaction Partner: COG3, DCTN4, MYH9, PRKAR1A, HAX1, SLC9A3R1, PDZK1, PRKAR2B, PRKAR2A,
Protein Size: 662

Molecular Weight: 71 kDa

Gene ID: 11216

NCBI Accession: NM_007202, NP_009133

UniProt: O43572

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling