GJA9 antibody (Middle Region)

Catalog No. ABIN2774869

Product Details anti-GJA9 Antibody

Target: GJA9 (Gap Junction Protein, alpha 9, 59kDa (GJA9))

Binding Specificity: Middle Region

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJA9 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IDGENNMRQS PQTVFSLPAN CDWKPRWLRA TWGSSTEHEN RGSPPKGNLK

Predicted Reactivity: Dog: 86%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against GJA9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GJA9

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 515 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GJA9 antibody (ABIN2774869)

Terrier-Lacombe, Guillou, Maire, Terrier, Vince, de Saint Aubain Somerhausen, Collin, Pedeutour, Coindre: "Dermatofibrosarcoma protuberans, giant cell fibroblastoma, and hybrid lesions in children: clinicopathologic comparative analysis of 28 cases with molecular data--a study from the French Federation of Cancer Centers Sarcoma Group." in: The American journal of surgical pathology, Vol. 27, Issue 1, pp. 27-39, (2002) (PubMed).

Target Details for GJA9

Target: GJA9 (Gap Junction Protein, alpha 9, 59kDa (GJA9))

Alternative Name: GJA9 (GJA9 Products)

Synonyms: CX58 antibody, CX59 antibody, GJA10 antibody, gap junction protein alpha 9 antibody, GJA9 antibody

Background: Connexins, such as GJA9, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.Connexins, such as GJA9, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-612 BI463634.1 7-618 613-1929 AF271261.1 585-1901 1930-2331 BU689816.1 1-402 c
Alias Symbols: CX58, CX59, GJA10, MGC50985
Protein Interaction Partner: GRB2,
Protein Size: 515

Molecular Weight: 59 kDa

Gene ID: 81025

NCBI Accession: NM_030772, NP_110399

UniProt: P57773