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GJC2 antibody (Middle Region)

GJC2 Reactivity: Human, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2774865
  • Target See all GJC2 Antibodies
    GJC2 (Gap Junction Protein, gamma 2, 47kDa (GJC2))
    Binding Specificity
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 20
    • 13
    • 11
    • 1
    • 1
    • 1
    Human, Rabbit
    Host
    • 16
    • 6
    Rabbit
    Clonality
    • 16
    • 6
    Polyclonal
    Conjugate
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GJC2 antibody is un-conjugated
    Application
    • 15
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    APASRTGSAT SAGTVGEQGR PGTHERPGAK PRAGSEKGSA SSRDGKTTVW
    Predicted Reactivity
    Human: 100%, Rabbit: 100%
    Characteristics
    This is a rabbit polyclonal antibody against GJC2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human GJC2
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 439 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    GJC2 (Gap Junction Protein, gamma 2, 47kDa (GJC2))
    Alternative Name
    GJC2 (GJC2 Products)
    Background
    GJC2 is a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.
    Alias Symbols: CX46.6, Cx47, GJA12, MGC105119, PMLDAR, HLD2, SPG44, LMPH1C
    Protein Interaction Partner: ALB,
    Protein Size: 439
    Molecular Weight
    47 kDa
    Gene ID
    57165
    NCBI Accession
    NM_020435, NP_065168
    UniProt
    Q5T442
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