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Annexin a1 antibody (N-Term)

ANXA1 Reactivity: Human, Mouse, Rat, Guinea Pig, Dog, Cow WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2774833
  • Target See all Annexin a1 (ANXA1) Antibodies
    Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
    Binding Specificity
    • 29
    • 15
    • 10
    • 10
    • 9
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 127
    • 47
    • 41
    • 10
    • 10
    • 9
    • 7
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Guinea Pig, Dog, Cow
    Host
    • 131
    • 34
    • 8
    • 1
    Rabbit
    Clonality
    • 139
    • 34
    Polyclonal
    Conjugate
    • 99
    • 27
    • 14
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Annexin a1 antibody is un-conjugated
    Application
    • 131
    • 65
    • 62
    • 26
    • 24
    • 24
    • 23
    • 22
    • 13
    • 13
    • 11
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    WFIENEEQEY VQTVKSSKGG PGSAVSPYPT FNPSSDVAAL HKAIMVKGVD
    Predicted Reactivity
    Cow: 79%, Dog: 79%, Guinea Pig: 79%, Human: 100%, Mouse: 83%, Rat: 82%
    Characteristics
    This is a rabbit polyclonal antibody against ANXA1. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA1
    Top Product
    Discover our top product ANXA1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 346 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ishida, Yamasaki, Yukizaki, Nishiyama, Tsubouchi, Okayama, Kataoka et al.: "Carnosol, rosemary ingredient, induces apoptosis in adult T-cell leukemia/lymphoma cells via glutathione depletion: proteomic approach using fluorescent two-dimensional differential gel ..." in: Human cell, Vol. 27, Issue 2, pp. 68-77, (2014) (PubMed).

    Nordon, Hinchliffe, Malkawi, Pirianov, Torsney, Loftus, Cockerill, Thompson: "Comparative proteomics reveals a systemic vulnerability in the vasculature of patients with abdominal aortic aneurysms." in: Journal of vascular surgery, Vol. 54, Issue 4, pp. 1100-1108.e6, (2011) (PubMed).

  • Target
    Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
    Alternative Name
    ANXA1 (ANXA1 Products)
    Synonyms
    anx1a antibody, anxa1 antibody, wu:fa01d11 antibody, wu:fa05d11 antibody, wu:fk69h01 antibody, MGC64363 antibody, anx1 antibody, lpc1 antibody, MGC89164 antibody, ANXA1 antibody, ANX1 antibody, LPC1 antibody, p35 antibody, Anx-1 antibody, Anx-A1 antibody, C430014K04Rik antibody, Lpc-1 antibody, Lpc1 antibody, Anx1 antibody, annexin A1a antibody, annexin A1 antibody, annexin A1 L homeolog antibody, Annexin A1 antibody, anxa1a antibody, anxa1 antibody, anxa1.L antibody, ANXA1 antibody, LOC100335033 antibody, Anxa1 antibody
    Background
    ANXA1 encodes a protein that belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
    Alias Symbols: ANX1, LPC1
    Protein Interaction Partner: UBC, MEIS2, SUMO2, SUMO3, WWOX, ZBTB1, HECW2, YWHAQ, ATP4A, UBD, BAG3, HMGA1, VCAM1, ITGA4, FN1, ATF2, ANXA4, RIPK1, IKBKG, RELA, CUL5, CDK2, SIRT7, ANXA5, ANXA1, KLHL23, LRIF1, OTUB1, C1orf123, CSAD, C14orf1, FAF1, COPS6, CCT7, KMT2B, UNC119, SUMO1, UBE2
    Protein Size: 346
    Molecular Weight
    38 kDa
    Gene ID
    301
    NCBI Accession
    NM_000700, NP_000691
    UniProt
    P04083
    Pathways
    Hormone Transport
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