RUFY1 antibody (C-Term)

Catalog No. ABIN2774789

Product Details anti-RUFY1 Antibody

Target: RUFY1 (RUN and FYVE Domain Containing 1 (RUFY1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Zebrafish (Danio rerio), Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUFY1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QCEKEFSISR RKHHCRNCGH IFCNTCSSNE LALPSYPKPV RVCDSCHTLL

Predicted Reactivity: Cow: 85%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against RUFY1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RUFY1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 600 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-RUFY1 antibody (ABIN2774789)

Suzuki, Fujisawa, Ando, Niino, Ohsawa, Shimokata, Ohta: "Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae." in: Neurology, Vol. 63, Issue 9, pp. 1711-3, (2004) (PubMed).

Target Details for RUFY1

Target: RUFY1 (RUN and FYVE Domain Containing 1 (RUFY1))

Alternative Name: RUFY1 (RUFY1 Products)

Synonyms: RABIP4 antibody, ZFYVE12 antibody, 3000002E04Rik antibody, Rabip4 antibody, rabip4 antibody, zfyve12 antibody, RUN and FYVE domain containing 1 antibody, RUN and FYVE domain containing 1 L homeolog antibody, RUFY1 antibody, Rufy1 antibody, rufy1 antibody, rufy1.L antibody

Background: RUFY1 contains 1 FYVE-type zinc finger and 1 RUN domain. It binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.
Alias Symbols: FLJ22251, RABIP4, ZFYVE12
Protein Interaction Partner: UBC, RAB3IP, RAB39B, TXNDC17, RUFY1, DIEXF, KLC4, PSME4, COPG1, COPZ1, TELO2, SART3, TTI1, COPB2, HCK, GIT2, PIAS2, TCF3, CCT8, VPS26A, RAB14, UBD, RABEP1, RAB5A, RAB4A, GRIK4, ITSN2, BMX, EPHA3,
Protein Size: 600

Molecular Weight: 69 kDa

Gene ID: 80230

NCBI Accession: NM_001040452, NP_001035542

UniProt: A8K7B1