FBXO11 antibody (Middle Region)

Catalog No. ABIN2774788

Product Details anti-FBXO11 Antibody

Target: FBXO11 (F-Box Protein 11 (FBXO11))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Zebrafish (Danio rerio), Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO11 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Sequence: HDVEFIRHDR FFCDCGAGTL SNPCTLAGEP THDTDTLYDS APPIESNTLQ

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXO11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 843 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO11

Target: FBXO11 (F-Box Protein 11 (FBXO11))

Alternative Name: FBXO11 (FBXO11 Products)

Synonyms: FBX11 antibody, PRMT9 antibody, UBR6 antibody, VIT1 antibody, C80048 antibody, Jf antibody, Vit1 antibody, fbxo11 antibody, MGC84634 antibody, FBXO11 antibody, im:6906507 antibody, wu:fj83f06 antibody, zgc:153171 antibody, Fbxo11 antibody, DKFZp459P2410 antibody, F-box protein 11 antibody, F-box protein 11 L homeolog antibody, F-box protein 11a antibody, F-box only protein 11 antibody, hypothetical protein antibody, FBXO11 antibody, Fbxo11 antibody, fbxo11.L antibody, fbxo11a antibody, CpipJ_CPIJ009919 antibody, CpipJ_CPIJ017549 antibody, Bm1_52225 antibody, LOAG_16571 antibody, fbxo11 antibody, LOC100115478 antibody

Background: FBXO11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for FBXO11.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: FBX11, FLJ12673, MGC44383, PRMT9, UG063H01, VIT1, UBR6
Protein Interaction Partner: SKP1, ERN1, DTL, CUL1, EED, UBC, NEDD8, COPS5, COPS6, ELAVL1, USP16, HDAC6, BCL6, RBX1, TP53,
Protein Size: 843

Molecular Weight: 94 kDa

Gene ID: 80204

NCBI Accession: NM_025133, NP_079409

UniProt: Q6DF73

Pathways: Sensory Perception of Sound