RNF128 antibody (C-Term)
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- Target See all RNF128 Antibodies
- RNF128 (Ring Finger Protein 128 (RNF128))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RNF128 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LEEHVQSTNE SLQLVNHEAN SVAVDVIPHV DNPTFEEDET PNQETAVREI
- Predicted Reactivity
- Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against RNF128. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human RNF128
- Top Product
- Discover our top product RNF128 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 428 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RNF128 (Ring Finger Protein 128 (RNF128))
- Alternative Name
- RNF128 (RNF128 Products)
- Synonyms
- rnf128 antibody, wu:fb57h05 antibody, zgc:77843 antibody, 1300002C13Rik antibody, AI987883 antibody, GRAIL antibody, Greul1 antibody, RGD1566282 antibody, grail antibody, greul1 antibody, ring finger protein 128a antibody, ring finger protein 128, E3 ubiquitin protein ligase antibody, ring finger protein 128 antibody, ring finger protein 128, E3 ubiquitin protein ligase L homeolog antibody, rnf128a antibody, RNF128 antibody, Rnf128 antibody, rnf128.L antibody
- Background
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RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of RNF128 in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of RNF128 was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype.The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: FLJ23516, GRAIL
Protein Interaction Partner: CEP76, APPBP2, TP53, UBE2H, UBE2E1, UBE2D1, Arhgdia, Arhgdib, RNF128, UBE2T, UBE2I, UBE2N, CD40LG, OTUB1, USP8,
Protein Size: 428 - Molecular Weight
- 47 kDa
- Gene ID
- 79589
- NCBI Accession
- NM_194463, NP_919445
- UniProt
- Q8TEB7
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