HERC6 antibody (N-Term)
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- Target See all HERC6 Antibodies
- HERC6 (HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6 (HERC6))
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Binding Specificity
- N-Term
- Reactivity
- Human, Mouse, Rat, Pig, Rabbit, Cow, Horse, Dog, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HERC6 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LSKDSQVFSW GKNSHGQLGL GKEFPSQASP QRVRSLEGIP LAQVAAGGAH
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against HERC6. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human HERC6
- Top Product
- Discover our top product HERC6 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1022 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HERC6 (HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6 (HERC6))
- Alternative Name
- HERC6 (HERC6 Products)
- Synonyms
- 1700121D12Rik antibody, 2510038N07Rik antibody, 4930427L17Rik antibody, AI451296 antibody, CEB1 antibody, Herc5 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 antibody, hect domain and RLD 6 antibody, HERC6 antibody, Herc6 antibody
- Background
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HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).
Alias Symbols: FLJ20637
Protein Interaction Partner: FUS, UBC, HSP90AA1, UBQLN2, HERC4, HERC3, NME2,
Protein Size: 1022 - Molecular Weight
- 115 kDa
- Gene ID
- 55008
- NCBI Accession
- NM_017912, NP_060382
- UniProt
- Q8IVU3
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