UBE2J1 antibody (N-Term)

Catalog No. ABIN2774737

Product Details anti-UBE2J1 Antibody

Target: UBE2J1 (Ubiquitin-Conjugating Enzyme E2, J1, U (UBE2J1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2J1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: METRYNLKSP AVKRLMKEAA ELKDPTDHYH AQPLEDNLFE WHFTVRGPPD

Predicted Reactivity: Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against UBE2J1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2J1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 318 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UBE2J1

Target: UBE2J1 (Ubiquitin-Conjugating Enzyme E2, J1, U (UBE2J1))

Alternative Name: UBE2J1 (UBE2J1 Products)

Synonyms: NCUBE1 antibody, ubc6p antibody, cgi-76 antibody, ncube1 antibody, hspc153 antibody, hspc205 antibody, hsu93243 antibody, HSPC153 antibody, HSPC205 antibody, HSU93243 antibody, NCUBE-1 antibody, UBC6 antibody, Ubc6p antibody, zgc:63554 antibody, UB2J1 antibody, 0710008M05Rik antibody, 1110030I22Rik antibody, Ncube antibody, Ncube1 antibody, ubiquitin conjugating enzyme E2 J1 antibody, ubiquitin-conjugating enzyme E2 J1 antibody, ubiquitin-conjugating enzyme E2, J1 antibody, ubiquitin conjugating enzyme E2 J1 L homeolog antibody, ubiquitin-conjugating enzyme E2J 1 antibody, UBE2J1 antibody, EDI_253240 antibody, MCYG_03847 antibody, ube2j1 antibody, ube2j1.L antibody, Ube2j1 antibody

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2J1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system.
Alias Symbols: CGI-76, HSPC153, HSPC205, HSU93243, MGC12555, NCUBE1, Ubc6p, UBC6, NCUBE-1
Protein Interaction Partner: UBC, UBA1, MAPKAPK2, OS9, RNF5, PARK2, DIO2, SOX6, TP53, AUP1, ASNA1, DERL3, DERL1, YOD1, DERL2, FAF2, VCP, SEL1L, ELAVL1, HLA-A, BIRC2, LRSAM1, TRIM63, SYVN1, TOPORS, PJA2, RNF2, TRIM27, BRCA1, BIRC3,
Protein Size: 318

Molecular Weight: 35 kDa

Gene ID: 51465

NCBI Accession: NM_016021, NP_057105

UniProt: Q9Y385