RNF19A antibody (N-Term)
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- Target See all RNF19A Antibodies
- RNF19A (Ring Finger Protein 19A (RNF19A))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Dog, Horse, Pig, Cow, Guinea Pig, Rabbit, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RNF19A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- IFSTNTSSDN GLTSISKQIG DFIECPLCLL RHSKDRFPDI MTCHHRSCVD
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against RNF19A. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human RNF19A
- Top Product
- Discover our top product RNF19A Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 838 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RNF19A (Ring Finger Protein 19A (RNF19A))
- Alternative Name
- RNF19A (RNF19A Products)
- Synonyms
- RNF19 antibody, RNF19A antibody, AA032313 antibody, Dorfin antibody, Rnf19 antibody, UIP117 antibody, Ubce7ip2 antibody, XYbp antibody, ring finger protein 19A, RBR E3 ubiquitin protein ligase antibody, ring finger protein 19A antibody, RNF19A antibody, Rnf19a antibody
- Background
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RNF19A contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB.The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported.
Alias Symbols: DKFZp566B1346, DORFIN, RNF19
Protein Interaction Partner: UBC, UBE2L3, Psmc3, ZAK, NUDT21, C11orf58, RPS6KA5, MAP3K7, ILK, SOD1, VCP, SNCAIP, CASR, UBE2E2, SUFU, TUBG2, UBE2L6, TUBG1,
Protein Size: 838 - Molecular Weight
- 91 kDa
- Gene ID
- 25897
- NCBI Accession
- NM_015435, NP_056250
- UniProt
- Q9NV58
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