TCF12 antibody (N-Term)

Catalog No. ABIN2774659

Product Details anti-TCF12 Antibody

Target: TCF12 (Transcription Factor 12 (TCF12))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Cow, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QQQRMAAIGT DKELSDLLDF SAMFSPPVNS GKTRPTTLGS SQFSGSGIDE

Cross-Reactivity: Cow (Bovine), Chicken, Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Cow: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against TCF12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TCF12

Application Details

Application Notes: WB Suggested Anti-TCF12 Antibody Titration: 0.06 µg/mL
ELISA Titer: 1:1562500
Positive Control: Human Lung.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 706 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TCF12

Target: TCF12 (Transcription Factor 12 (TCF12))

Alternative Name: TCF12 (TCF12 Products)

Background: TCF12 encodes a protein that is a member of the basic helix-loop-helix (bHLH) E-protein family which recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins.The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Alias Symbols: HEB, HTF4, HsT17266, bHLHb20
Protein Interaction Partner: TSNAX, STAT5A, SRI, RNASEL, QARS, PSMA1, MLLT6, ID3, CDKN2C, TRIM72, LYSMD1, C6orf165, HEXIM2, ASCL4, MORN4, TWIST2, C16orf45, HOPX, NAGK, C1orf109, SPG21, VPS28, NEUROG3, OSGIN1, CRCP, EDRF1, ARMC8, MAPKBP1, STK16, DGCR6, UBC, TCF21, SOX2, ID2, BMF, MYC,
Protein Size: 706

Molecular Weight: 73 kDa

Gene ID: 6938

NCBI Accession: NM_207036, NP_996919

UniProt: Q99081

Pathways: SARS-CoV-2 Protein Interactome