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ADAR antibody (C-Term)

ADAR Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2774647
  • Target See all ADAR Antibodies
    ADAR (Adenosine Deaminase, RNA-Specific (ADAR))
    Binding Specificity
    • 15
    • 15
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat, Rabbit, Guinea Pig, Horse
    Host
    • 74
    • 4
    • 1
    Rabbit
    Clonality
    • 67
    • 12
    Polyclonal
    Conjugate
    • 29
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ADAR antibody is un-conjugated
    Application
    • 51
    • 27
    • 27
    • 18
    • 13
    • 11
    • 7
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    RMGFTEVTPV TGASLRRTML LLSRSPEAQP KTLPLTGSTF HDQIAMLSHR
    Predicted Reactivity
    Guinea Pig: 92%, Horse: 92%, Human: 92%, Mouse: 91%, Rabbit: 92%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against ADAR. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human ADAR
    Top Product
    Discover our top product ADAR Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1226 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Pan, Ye, Franco, Li, Yu, Zou, Zhang, Jiao, Lin: "Insulin resistance and depressive symptoms in middle-aged and elderly Chinese: findings from the Nutrition and Health of Aging Population in China Study." in: Journal of affective disorders, Vol. 109, Issue 1-2, pp. 75-82, (2008) (PubMed).

  • Target
    ADAR (Adenosine Deaminase, RNA-Specific (ADAR))
    Alternative Name
    ADAR (ADAR Products)
    Background
    ADAR is responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: ADAR1, DRADA, DSH, DSRAD, G1P1, IFI-4, IFI4, K88dsRBP, p136, P136, K88DSRBP
    Protein Interaction Partner: UBC, SUMO2, SUMO3, STAU1, STAU2, SUMO1, RPA3, RPA2, RPA1, ERG, SUZ12, EED, EZH2, BMI1, RNF2, rev, FBXO6, TARDBP, UBE2I, HDAC9, XPO1, WHSC1, TGM2, SNRPN, SNRPB, UPF1, DHX9, DDX17, HNRNPM, CAND1, CUL3, HNRNPA1, ELAVL1, HDAC5, tat, ADAR, HDLBP,
    Protein Size: 1226
    Molecular Weight
    136 kDa
    Gene ID
    103
    NCBI Accession
    NM_001111, NP_001102
    UniProt
    P55265
    Pathways
    Protein targeting to Nucleus
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