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RGS11 antibody (Middle Region)

RGS11 Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2774606
  • Target See all RGS11 Antibodies
    RGS11 (Regulator of G-Protein Signaling 11 (RGS11))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 1
    • 1
    Middle Region
    Reactivity
    • 26
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
    Host
    • 25
    • 1
    Rabbit
    Clonality
    • 26
    Polyclonal
    Conjugate
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RGS11 antibody is un-conjugated
    Application
    • 18
    • 14
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LRQPHRYVLD DAQLHIYMLM KKDSYPRFLK SDMYKALLAE AGIPLEMKRR
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%
    Characteristics
    This is a rabbit polyclonal antibody against RGS11. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human RGS11
    Top Product
    Discover our top product RGS11 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 446 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RGS11 (Regulator of G-Protein Signaling 11 (RGS11))
    Alternative Name
    RGS11 (RGS11 Products)
    Synonyms
    RS11 antibody, C78048 antibody, XRGSIV antibody, rgs9-a antibody, regulator of G protein signaling 11 antibody, regulator of G-protein signaling 11 antibody, regulator of G-protein signaling 11 L homeolog antibody, RGS11 antibody, Rgs11 antibody, rgs11.L antibody
    Background
    RGS11 belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form.The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
    Alias Symbols: RS11
    Protein Interaction Partner: GNB5, ADRB2, SNTA1, HSP90AA1,
    Protein Size: 446
    Molecular Weight
    51 kDa
    Gene ID
    8786
    NCBI Accession
    NM_003834, NP_003825
    UniProt
    Q4TT72
    Pathways
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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