RAP2A antibody (N-Term)

Catalog No. ABIN2774388

Product Details anti-RAP2A Antibody

Target: RAP2A (RAP2A, Member of RAS Oncogene Family (RAP2A))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Zebrafish (Danio rerio), Cow, Guinea Pig, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAP2A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KYDPTIEDFY RKEIEVDSSP SVLEILDTAG TEQFASMRDL YIKNGQGFIL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against RAP2A. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 183 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAP2A

Target: RAP2A (RAP2A, Member of RAS Oncogene Family (RAP2A))

Alternative Name: RAP2A (RAP2A Products)

Synonyms: krev antibody, rap2 antibody, k-rev antibody, rbbp-30 antibody, RAP2A antibody, K-REV antibody, KREV antibody, RAP2 antibody, RbBP-30 antibody, 5830461H18Rik antibody, RAP2A, member of RAS oncogene family antibody, Rap2A GTPase antibody, RAP2B, member of RAS oncogene family antibody, RAS related protein 2a antibody, RAP2A antibody, Rap2a antibody, rap2a antibody, RAP2B antibody

Background: RAP2A is a small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.
Alias Symbols: K-REV, KREV, RAP2, RbBP-30
Protein Interaction Partner: UBC, RPTOR, ELAVL1, RRP9, TM7SF2, PLG, SERPINA1, FTL, FKBP2, ENSA, EEF1A1, NEDD4, TNIK, RUNDC3A, GRIN1, RASIP1, RAPGEF5, RAPGEF6, ARHGAP29, RASSF5, MAP4K4, BMPR1B, GRIN2D, RGS14, RALGDS, SMAD1, TGFBR1, RAP2A, RAF1, MLLT4, FNTB, ACVR1, RAPGEF4, RAPGEF3, RA
Protein Size: 183

Molecular Weight: 20 kDa

Gene ID: 5911

NCBI Accession: NM_021033, NP_066361

UniProt: P10114