PRPF18 antibody (Middle Region)

Catalog No. ABIN2774355

Product Details anti-PRPF18 Antibody

Target: PRPF18 (PRP18 Pre-mRNA Processing Factor 18 (PRPF18))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRPF18 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NKGLRNDLKA ALDKIDQQYL NEIVGGQEPG EEDTQNDLKV HEENTTIEEL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PRPF18. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PRPF18

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRPF18

Target: PRPF18 (PRP18 Pre-mRNA Processing Factor 18 (PRPF18))

Alternative Name: PRPF18 (PRPF18 Products)

Synonyms: PRP18 antibody, hPrp18 antibody, Pprf18 antibody, 2810441A10Rik antibody, zgc:91830 antibody, pre-mRNA processing factor 18 antibody, pre-mRNA processing factor 18 L homeolog antibody, PRP18 pre-mRNA processing factor 18 homolog (yeast) antibody, PRPF18 antibody, Prpf18 antibody, prpf18.L antibody, prpf18 antibody

Background: Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18.
Alias Symbols: PRP18, hPrp18
Protein Interaction Partner: UBC, LSM4, SUMO2, PPIH,
Protein Size: 342

Molecular Weight: 40 kDa

Gene ID: 8559

NCBI Accession: NM_003675, NP_003666

UniProt: Q99633