CFHR1 antibody (N-Term)
-
- Target See all CFHR1 Antibodies
- CFHR1 (Complement Factor H-Related 1 (CFHR1))
-
Binding Specificity
- N-Term
-
Reactivity
- Human, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This CFHR1 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- NHGILYDEEK YKPFSQVPTG EVFYYSCEYN FVSPSKSFWT RITCTEEGWS
- Predicted Reactivity
- Human: 100%, Rat: 77%
- Characteristics
- This is a rabbit polyclonal antibody against CFHR1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product CFHR1 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 330 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- CFHR1 (Complement Factor H-Related 1 (CFHR1))
- Alternative Name
- CFHR1 (CFHR1 Products)
- Synonyms
- AI194696 antibody, CFHRB antibody, Cfhl1 antibody, CFHL antibody, CFHL1 antibody, CFHL1P antibody, CFHR1P antibody, FHR1 antibody, H36-1 antibody, H36-2 antibody, HFL1 antibody, HFL2 antibody, complement factor H-related 1 antibody, complement factor H-related protein 1 antibody, complement factor H related 1 antibody, Cfhr1 antibody, LOC735590 antibody, LOC746429 antibody, CFHR1 antibody
- Background
-
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
Alias Symbols: CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2, MGC104329
Protein Interaction Partner: PRDX4, LBP, APOA1, CFH,
Protein Size: 330 - Molecular Weight
- 36 kDa
- Gene ID
- 3078
- NCBI Accession
- NM_002113, NP_002104
- UniProt
- Q03591
-