PPP1R15B antibody (C-Term)

Catalog No. ABIN2774292

Product Details anti-PPP1R15B Antibody

Target: PPP1R15B (Protein Phosphatase 1, Regulatory Subunit 15B (PPP1R15B))

Binding Specificity: C-Term

Reactivity: Human, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R15B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SFCSVDPYNP QNFTATIQTA ARIVPEEPSD SEKDLSGKSD LENSSQSGSL

Predicted Reactivity: Cow: 92%, Dog: 91%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against PPP1R15B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PPP1R15B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 713 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP1R15B

Target: PPP1R15B (Protein Phosphatase 1, Regulatory Subunit 15B (PPP1R15B))

Alternative Name: PPP1R15B (PPP1R15B Products)

Synonyms: 1810033K10Rik antibody, AI606441 antibody, C530022L24Rik antibody, CReP antibody, CREP antibody, protein phosphatase 1, regulatory (inhibitor) subunit 15b antibody, protein phosphatase 1 regulatory subunit 15B antibody, protein phosphatase 1, regulatory subunit 15B antibody, Ppp1r15b antibody, PPP1R15B antibody

Background: PPP1R15B promotes dephosphorylation of the transcription initiation factor EIF2-alpha through recruitment of protein phosphatase-1 (PP1) catalytic subunits.
Alias Symbols: CREP, FLJ14744
Protein Interaction Partner: FBXW11, UBC, PPP1CC, PPP1CA, RAD21,
Protein Size: 713

Molecular Weight: 79 kDa

Gene ID: 84919

NCBI Accession: NM_032833, NP_116222

UniProt: Q5SWA1

Pathways: ER-Nucleus Signaling