PAR1 antibody (C-Term)
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- Target See all PAR1 (F2R) Antibodies
- PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Mouse, Pig, Dog, Horse, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PAR1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- YAYYFSAFSA VFFFVPLIIS TVCYVSIIRC LSSSAVANRS KKSRALFLSA
- Predicted Reactivity
- Dog: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 85%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against F2R. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human F2R
- Top Product
- Discover our top product F2R Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 425 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
- Alternative Name
- F2R (F2R Products)
- Synonyms
- CF2R antibody, HTR antibody, PAR-1 antibody, PAR1 antibody, TR antibody, Par1 antibody, TRGPC antibody, AI482343 antibody, Cf2r antibody, ThrR antibody, Par-1 antibody, f2r-a antibody, par1 antibody, coagulation factor II thrombin receptor antibody, coagulation factor II (thrombin) receptor antibody, coagulation factor 2 (thrombin) receptor L homeolog antibody, F2R antibody, F2r antibody, f2r.L antibody
- Background
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Coagulation factor II receptor(F2R) is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member.
Alias Symbols: CF2R, HTR, PAR-1, PAR1, TR
Protein Interaction Partner: UBC, PROCR, CAV1, CHRD, ATP13A2, PDCD6IP, AP3D1, GNAQ, GNAI2, FLOT2, CHMP4A, GNAT1, GNA13, GNA12, SNX1, GPRASP1, ITGAV, PRTN3, F2, PLG, GNA15, ELANE, CTSG, CAPN1, MMP1,
Protein Size: 425 - Molecular Weight
- 47 kDa
- Gene ID
- 2149
- NCBI Accession
- NM_001992, NP_001983
- UniProt
- P25116
- Pathways
- Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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