USP47 antibody (Middle Region)

Catalog No. ABIN2774253

Product Details anti-USP47 Antibody

Target: USP47 (Ubiquitin Specific Peptidase 47 (USP47))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rabbit, Cow, Dog, Horse, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP47 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SITSSRRTKA NEGKKETWDT AEEDSGTDSE YDESGKSRGE MQYMYFKAEP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against USP47. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human USP47

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1287 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for USP47

Target: USP47 (Ubiquitin Specific Peptidase 47 (USP47))

Alternative Name: USP47 (USP47 Products)

Synonyms: USP47 antibody, zgc:165650 antibody, TRFP antibody, 4930502N04Rik antibody, A630020C16Rik antibody, ubiquitin specific peptidase 47 antibody, ubiquitin carboxyl-terminal hydrolase 47 antibody, ubiquitin specific peptidase 47 S homeolog antibody, Usp47 antibody, USP47 antibody, usp47 antibody, LOC100639726 antibody, usp47.S antibody

Background: USP47 is a putative ubiquitin-specific-processing protease that regulates cell growth and survival. USP47 probably regulates CDC25A expression at a transcriptional level. USP47 may be catalytically inactive although it seems to have kept all necessary active site residues.
Alias Symbols: DKFZp686C13257, FLJ20727, TRFP
Protein Interaction Partner: KIFC3, FBXW11, AP4M1, BTRC, UBC, WDR44, ATP6V1H, GMPPB, PDXDC1, KATNA1, HDAC6, SNCA, GRK5, SIRT7, PLA2G2A, MED9, MED29,
Protein Size: 1287

Molecular Weight: 147 kDa

Gene ID: 55031

NCBI Accession: NM_017944, NP_060414

UniProt: B3KXF5

Pathways: Negative Regulation of intrinsic apoptotic Signaling