ATG3 antibody (Middle Region)

Catalog No. ABIN2774245

Product Details anti-ATG3 Antibody

Target: ATG3 (ATG3 Autophagy Related 3 (ATG3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SDELEAIIEE DDGDGGWVDT YHNTGITGIT EAVKEITLEN KDNIRLQDCS

Predicted Reactivity: Cow: 79%, Dog: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ATG3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATG3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 314 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATG3

Target: ATG3 (ATG3 Autophagy Related 3 (ATG3))

Alternative Name: ATG3 (ATG3 Products)

Synonyms: atg3 antibody, im:6910145 antibody, wu:fb15g12 antibody, zgc:64156 antibody, APG3 antibody, APG3-LIKE antibody, APG3L antibody, PC3-96 antibody, 2610016C12Rik antibody, Apg3l antibody, Atg3l antibody, PIG-1 antibody, Pig1 antibody, ATATG3 antibody, K11J9.1 antibody, K11J9_1 antibody, autophagy related 3 antibody, autophagy 3 (APG3) antibody, similar to S. cerevisiae ATG3 (YNR007C) part of ubiquitin-like system that mediates Atg8-phosphatidylethanolamine conjugation required for protein-vacuolar targeting and autophagy antibody, atg3 antibody, ATG3 antibody, Atg3 antibody

Background: Autophagy is a process of bulk degradation of cytoplasmic components by the lysosome or vacuole. Human ATG3 displays the same enzymatic characteristics in vitro as yeast Apg3, a protein-conjugating enzyme essential for autophagy (Tanida et al., 2002 [PubMed 11825910]).
Alias Symbols: APG3, APG3-LIKE, APG3L, DKFZp564M1178, FLJ22125, MGC15201, PC3-96
Protein Interaction Partner: HUWE1, MAP1LC3B, UBC, SUMO1, NEDD8, ATG7, ATG5, ATG12, BECN1, HSPA9, DFFA, ASS1, NHLRC2, NANS, TNFAIP8, RPL23, BAG3, FNBP1L, GABARAPL1, MAP1LC3A, CFLAR, CREBBP, MAP1LC3C, ATG10, AMBRA1, ATG16L1, TECPR1, OBSL1, ATG4B, GABARAPL2, GABARAP, MAP1B, KRT85,
Protein Size: 314

Molecular Weight: 36 kDa

Gene ID: 64422

NCBI Accession: NM_022488, NP_071933

UniProt: Q9NT62

Pathways: Autophagy