PHYH antibody (N-Term)

Catalog No. ABIN2774157

Product Details anti-PHYH Antibody

Target: PHYH (Phytanoyl-CoA 2-Hydroxylase (PHYH))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHYH antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TLPEILKYVE CFTGPNIMAM HTMLINKPPD SGKKTSRHPL HQDLHYFPFR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PHYH. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PHYH

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 338 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHYH

Target: PHYH (Phytanoyl-CoA 2-Hydroxylase (PHYH))

Alternative Name: PHYH (PHYH Products)

Synonyms: zgc:110203 antibody, LN1 antibody, LNAP1 antibody, PAHX antibody, PHYH1 antibody, RD antibody, AI256161 antibody, AI265699 antibody, Lnap1 antibody, phytanoyl-CoA 2-hydroxylase antibody, phytanoyl-CoA hydroxylase-like antibody, phytanoyl-CoA hydroxylase antibody, PHYH antibody, LOC478001 antibody, phyh antibody, Phyh antibody

Background: This gene is a member of the PhyH family and encodes a peroxisomal protein that is involved in the alpha-oxidation of 3-methyl branched fatty acids. Specifically, this protein converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Mutations in this gene have been associated with Refsum disease (RD) and deficient protein activity has been associated with Zellweger syndrome and rhizomelic chondrodysplasia punctata. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: LN1, LNAP1, PAHX, PHYH1, RD
Protein Interaction Partner: FAM9B, UBC, APP, ELAVL1, PHYHIP, FKBP4, ACSL6, TOM1L1, PHYH, PEX7, F8, MAGEA11, WRAP73, COPS3,
Protein Size: 338

Molecular Weight: 39 kDa

Gene ID: 5264

NCBI Accession: NM_001037537, NP_001032626

UniProt: O14832

Pathways: Monocarboxylic Acid Catabolic Process