SFRS7 antibody (N-Term)

Catalog No. ABIN2774137

Product Details anti-SFRS7 Antibody

Target: SFRS7 (Splicing Factor, Arginine/Serine Rich 7 (SFRS7))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFRS7 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSRYGRYGGE TKVYVGNLGT GAGKGELERA FSYYGPLRTV WIARNPPGFA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SFRS7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SFRS7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 238 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SFRS7 antibody (ABIN2774137)

Swartz, Bor, Misawa, Rekosh, Hammarskjold: "The shuttling SR protein 9G8 plays a role in translation of unspliced mRNA containing a constitutive transport element." in: The Journal of biological chemistry, Vol. 282, Issue 27, pp. 19844-53, (2007) (PubMed).

Target Details for SFRS7

Target: SFRS7 (Splicing Factor, Arginine/Serine Rich 7 (SFRS7))

Alternative Name: SFRS7 (SFRS7 Products)

Synonyms: 9G8 antibody, AAG3 antibody, SFRS7 antibody, 35kDa antibody, 9430065L19Rik antibody, NX-96 antibody, Sfrs7 antibody, 9g8 antibody, aag3 antibody, sfrs7 antibody, srsf7 antibody, zgc:114203 antibody, serine and arginine rich splicing factor 7 antibody, serine/arginine-rich splicing factor 7 antibody, serine/arginine-rich splicing factor 7 L homeolog antibody, serine/arginine-rich splicing factor 7b antibody, SRSF7 antibody, Srsf7 antibody, srsf7.L antibody, srsf7b antibody

Background: SFRS7 is required for pre-mRNA splicing. SFRS7 can also modulate alternative splicing in vitro.
Alias Symbols: 9G8, AAG3, HSSG1, RBM37, ZCCHC20, ZCRB2, SFRS7
Protein Interaction Partner: LUC7L2, SDCBP, RELA, CEP250, UBC, STAU1, ZBTB1, EZH2, SUZ12, EED, NEDD4, TARDBP, CLK3, SRPK2, SRPK1, YWHAE, PAN2, CDK6, MAGOH, EIF4A3, HNF1A, ESR1, BARD1, PAXIP1, ZRANB2, TM9SF2, SRSF11, DDX21, PRPF3, SART1, BUD31, U2AF1, TFPI, SURF4, SON, SNRPA1, TRA2B,
Protein Size: 238

Molecular Weight: 27 kDa

Gene ID: 6432

NCBI Accession: NM_001031684, NP_001026854

UniProt: Q16629