PROS1 antibody (Middle Region)

Catalog No. ABIN2774131

Product Details anti-PROS1 Antibody

Target: PROS1 (PROS) (Protein S (PROS))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Dog, Horse, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PROS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MCAQLCVNYP GGYTCYCDGK KGFKLAQDQK SCEVVSVCLP LNLDTKYELL

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PROS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PROS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 676 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PROS1 antibody (ABIN2774131)

Ten Kate, Platteel, Mulder, Terpstra, Nicolaes, Reitsma, van der Steege, van der Meer: "PROS1 analysis in 87 pedigrees with hereditary protein S deficiency demonstrates striking genotype-phenotype associations." in: Human mutation, Vol. 29, Issue 7, pp. 939-47, (2008) (PubMed).

Target Details for PROS1

Target: PROS1 (PROS) (Protein S (PROS))

Alternative Name: PROS1 (PROS Products)

Synonyms: PROS antibody, PS21 antibody, PS22 antibody, PS23 antibody, PS24 antibody, PS25 antibody, PSA antibody, THPH5 antibody, THPH6 antibody, zgc:154001 antibody, AW214361 antibody, protein S antibody, protein S (alpha) antibody, PROS1 antibody, Pros1 antibody, pros1 antibody

Background: PROS1 is an anticoagulant plasma protein, it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
Alias Symbols: PROS, PS 26, PS21, PS22, PS23, PS24, PS25, PSA
Protein Interaction Partner: FBXO6, NPM1, TBK1, RPSA, C4BPA, TYRO3, F8, F10, F5, F2, PROC, C4BPB,
Protein Size: 676

Molecular Weight: 71 kDa

Gene ID: 5627

NCBI Accession: NM_000313, NP_000304

UniProt: P07225