DSTYK antibody (Middle Region)

Catalog No. ABIN2774127

Product Details anti-DSTYK Antibody

Target: DSTYK (Dual serine/threonine and tyrosine Protein Kinase (DSTYK))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DSTYK antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EECWQLMEAC WDGDPLKRPL LGIVQPMLQG IMNRLCKSNS EQPNRGLDDS

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 86%, Rabbit: 85%, Rat: 90%

Characteristics: This is a rabbit polyclonal antibody against RIPK5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RIPK5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 884 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-DSTYK antibody (ABIN2774127)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for DSTYK

Target: DSTYK (Dual serine/threonine and tyrosine Protein Kinase (DSTYK))

Alternative Name: RIPK5 (DSTYK Products)

Synonyms: CAKUT1 antibody, DustyPK antibody, RIP5 antibody, RIPK5 antibody, A930019K20Rik antibody, C430014H23Rik antibody, C820013G01 antibody, Ripk5 antibody, ripk5 antibody, zgc:136421 antibody, DSTYK antibody, GB11994 antibody, DUSTYPK antibody, dual serine/threonine and tyrosine protein kinase antibody, receptor interacting protein kinase 5 antibody, dual serine/threonine and tyrosine protein kinase S homeolog antibody, DSTYK antibody, Dstyk antibody, dstyk antibody, Ripk5 antibody, dstyk.S antibody

Background: RIPK5 may induce both caspase-dependent apoptosis and caspase-independent cell death.This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. Multiple alternatively spliced transcript variants have been found, but the biological validity of some variants has not been determined.
Alias Symbols: DustyPK, HDCMD38P, KIAA0472, RIP5, RIPK5
Protein Interaction Partner: RAB5C, PSMB3, PSMB1, MAD2L1, HSPE1, UBE2K, DDT, ATP5F1, MTPN, LSM12, RAB14, IKBKE, RPS9,
Protein Size: 884

Molecular Weight: 100 kDa

Gene ID: 25778

NCBI Accession: NM_199462, NP_955749