GZMA antibody (Middle Region)
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- Target See all GZMA Antibodies
- GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GZMA antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TREGDLKLLQ LTEKAKINKY VTILHLPKKG DDVKPGTMCQ VAGWGRTHNS
- Predicted Reactivity
- Cow: 85%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against GZMA. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human GZMA
- Top Product
- Discover our top product GZMA Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 262 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))
- Alternative Name
- GZMA (GZMA Products)
- Synonyms
- gzmA antibody, GZMA antibody, AW494114 antibody, Ctla-3 antibody, Ctla3 antibody, Hf antibody, SE1 antibody, TSP-1 antibody, TSP1 antibody, CTLA3 antibody, HFSP antibody, granzyme A antibody, Granzyme A antibody, granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) antibody, gzmA antibody, GZMA antibody, graa antibody, Gzma antibody
- Background
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Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CTLA3, HFSP
Protein Interaction Partner: HSP90AA1, HSPA4, HMGB2, APEX1, XRCC5, XRCC6, HIST2H2BE, SET, LMNA, HNRNPK, HDC, HIST1H1A, GZMA, GOLGA2, ACTG1, Ndufs3, NCL, LMNB1,
Protein Size: 262 - Molecular Weight
- 29 kDa
- Gene ID
- 3001
- NCBI Accession
- NM_006144, NP_006135
- UniProt
- P12544
- Pathways
- Apoptosis
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