FEM1B antibody (C-Term)
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- Target See all FEM1B Antibodies
- FEM1B (Fem-1 Homolog B (FEM1B))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FEM1B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- DKSTTGVSEI LLKTQMKMSL KCLAARAVRA NDINYQDQIP RTLEEFVGFH
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against FEM1B. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human FEM1B
- Top Product
- Discover our top product FEM1B Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 627 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FEM1B (Fem-1 Homolog B (FEM1B))
- Alternative Name
- FEM1B (FEM1B Products)
- Synonyms
- F1A-ALPHA antibody, F1AA antibody, FEM1-beta antibody, FEM1B antibody, mKIAA0396 antibody, fem-1 homolog B antibody, protein fem-1 homolog B antibody, fem-1 homolog B L homeolog antibody, fem-1 homolog b (C. elegans) antibody, feminization 1 homolog b (C. elegans) antibody, FEM1B antibody, Fem1b antibody, LOC413692 antibody, fem1b.L antibody, fem1b antibody
- Background
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FEM1B is a component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. It involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. FEM1B also involved in glucose homeostasis in pancreatic islet.
Alias Symbols: DKFZp451E0710, FIAA, F1A-ALPHA
Protein Interaction Partner: GLI1, HIF1AN, NKX3-1, fem-2, Ppm1f, UBC, RBX1, CUL2, TCEB2, TCEB1, Tnfrsf1a, Fem1b, Fas, Casp3, COPS4, RAD9A, CHEK1, DCUN1D1, COPS5, COPS6, CUL5, NEDD8, KIAA0319, GNB2L1, APAF1,
Protein Size: 627 - Molecular Weight
- 69 kDa
- Gene ID
- 10116
- NCBI Accession
- NM_015322, NP_056137
- UniProt
- Q9UK73
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