CCT6B antibody (N-Term)

Catalog No. ABIN2774055

Product Details anti-CCT6B Antibody

Target: CCT6B (T-Complex Protein 1 Subunit zeta-2-Like (CCT6B))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCT6B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VARTSLQTKV HAELADVLTE VVVDSVLAVR RPGYPIDLFM VEIMEMKHKL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against CCT6B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CCT6B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 530 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCT6B

Target: CCT6B (T-Complex Protein 1 Subunit zeta-2-Like (CCT6B))

Alternative Name: CCT6B (CCT6B Products)

Synonyms: CCT-zeta-2 antibody, CCTZ-2 antibody, Cctz2 antibody, TCP-1-zeta-2 antibody, TSA303 antibody, CCTzeta-2 antibody, Cctz-2 antibody, chaperonin containing TCP1 subunit 6B antibody, T-complex protein 1 subunit zeta-2-like antibody, t-complex protein 1 subunit zeta-2-like antibody, chaperonin containing Tcp1, subunit 6b (zeta) antibody, CCT6B antibody, Cct6b antibody, LOC100445522 antibody, LOC100616822 antibody

Background: CCT6B is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin.This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Alias Symbols: CCT-zeta-2, CCTZ-2, Cctz2, TCP-1-zeta-2, TSA303
Protein Interaction Partner: UBC, FAM86B2, METTL18, METTL21B, PAXIP1, CCT5, CCT2, CCT4, CCT3, TCP1, EIF4B, UBASH3B, FBXW8, PPP2R2D, STRN,
Protein Size: 530

Molecular Weight: 58 kDa

Gene ID: 10693

NCBI Accession: NM_006584, NP_006575

UniProt: Q92526