HUS1B antibody (N-Term)

Catalog No. ABIN2774030

Product Details anti-HUS1B Antibody

Target: HUS1B (HUS1 Checkpoint Homolog B (HUS1B))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HUS1B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ELFIHVSGTV ARLAKVCVLR VRPDSLCFGP AGSGGLHEAR LWCEVRQGAF

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against HUS1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HUS1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 278 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HUS1B

Target: HUS1B (HUS1 Checkpoint Homolog B (HUS1B))

Alternative Name: HUS1B (HUS1B Products)

Synonyms: HUS1B antibody, RP11-532F6.1 antibody, HUS1 checkpoint clamp component B antibody, HUS1B antibody, Hus1b antibody

Background: HUS1Bis most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. HUS1B can interact with the check point protein RAD1 but not with RAD9. Overexpression of HUS1B has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.
Alias Symbols: MGC126746, MGC126748, RP11-532F6.1
Protein Interaction Partner: RAD9B, RAD9A, HUS1, RAD1,
Protein Size: 278

Molecular Weight: 31 kDa

Gene ID: 135458

NCBI Accession: NM_148959, NP_683762

UniProt: Q8NHY5