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PRTFDC1 antibody (Middle Region)

PRTFDC1 Reactivity: Human, Rat, Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2773930
  • Target See all PRTFDC1 Antibodies
    PRTFDC1 (phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Rat, Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio)
    Host
    • 50
    • 2
    Rabbit
    Clonality
    • 52
    Polyclonal
    Conjugate
    • 18
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRTFDC1 antibody is un-conjugated
    Application
    • 40
    • 21
    • 13
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MKALLSNIEK YKPNMIKVAS LLVKRTSRSD GFRPDYAGFE IPNLFVVGYA
    Predicted Reactivity
    Dog: 92%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 77%, Rat: 92%, Zebrafish: 77%
    Characteristics
    This is a rabbit polyclonal antibody against PRTFDC1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human PRTFDC1
    Top Product
    Discover our top product PRTFDC1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 225 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Suzuki, Imoto, Pimkhaokham, Nakagawa, Kamata, Kozaki, Amagasa, Inazawa: "PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation." in: Oncogene, Vol. 26, Issue 57, pp. 7921-32, (2007) (PubMed).

  • Target
    PRTFDC1 (phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))
    Alternative Name
    PRTFDC1 (PRTFDC1 Products)
    Synonyms
    HHGP antibody, HPRT antibody, hprt1 antibody, hprt1l antibody, zgc:55561 antibody, zgc:86771 antibody, MGC80959 antibody, OTTMUSG00000011667 antibody, Prtfdc1 antibody, phosphoribosyl transferase domain containing 1 antibody, phosphoribosyl transferase domain containing 1 L homeolog antibody, phosphoribosyltransferase domain containing 1 pseudogene antibody, PRTFDC1 antibody, prtfdc1 antibody, Prtfdc1 antibody, prtfdc1.L antibody, Gm13377 antibody
    Background
    PRTFDC1 belongs to the purine/pyrimidine phosphoribosyltransferase family. Epigenetic silencing of PRTFDC1 by hypermethylation of the CpG islands leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis.
    Alias Symbols: FLJ11888, HHGP
    Protein Interaction Partner: LGALS9B, EEF2KMT, MCMBP, GNPDA1, EPM2AIP1, TCL1A, HPRT1, UBC, RTN3, FLAD1, NIF3L1, DTNB, STAT5A, EWSR1,
    Protein Size: 225
    Molecular Weight
    26 kDa
    Gene ID
    56952
    NCBI Accession
    NM_020200, NP_064585
    UniProt
    Q9NRG1
    Pathways
    Ribonucleoside Biosynthetic Process
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