Peroxiredoxin 6 antibody (Middle Region)

Catalog No. ABIN2773916

Product Details anti-Peroxiredoxin 6 Antibody

Target: Peroxiredoxin 6 (PRDX6)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio), Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ARVVFVFGPD KKLKLSILYP ATTGRNFDEI LRVVISLQLT AEKRVATPVD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PRDX6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PRDX6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 224 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Peroxiredoxin 6

Target: Peroxiredoxin 6 (PRDX6)

Alternative Name: PRDX6 (PRDX6 Products)

Background: PRDX6 is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell, it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell, it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: 1-Cys, AOP2, KIAA0106, MGC46173, NSGPx, PRX, aiPLA2, p29
Protein Interaction Partner: HUWE1, CASP10, CASP8, STAU1, UBC, NEDD8, MDM2, ASB12, ASB3, NPM1, CDK2, PRDX6, VCAM1, ORM2, ITGA4, NR4A1, GPX4, FN1, PAXIP1, TMEM189, NIT2, SSU72, TIMM9, PRDX5, TMED10, C11orf58, PITRM1, SUCLG2, TPI1, PRDX2, RDX, RANGAP1, PKM, PFAS, PRDX1, MDH1, ATP6V1A,
Protein Size: 224

Molecular Weight: 25 kDa

Gene ID: 9588

NCBI Accession: NM_004905, NP_004896

UniProt: P30041