IGFBP7 antibody (C-Term)

Catalog No. ABIN2773913

Product Details anti-IGFBP7 Antibody

Target: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Sheep, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGFBP7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RGGPEKHEVT GWVLVSPLSK EDAGEYECHA SNSQGQASAS AKITVVDALH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against IGFBP7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human IGFBP7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 282 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IGFBP7

Target: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Alternative Name: IGFBP7 (IGFBP7 Products)

Synonyms: zgc:85888 antibody, AGM antibody, FSTL2 antibody, IBP-7 antibody, IGFBP-7 antibody, IGFBP-7v antibody, IGFBPRP1 antibody, MAC25 antibody, PSF antibody, RAMSVPS antibody, TAF antibody, Fstl2 antibody, Mac25 antibody, insulin like growth factor binding protein 7 antibody, insulin-like growth factor binding protein 7 antibody, IGFBP7 antibody, igfbp7 antibody, Igfbp7 antibody

Background: IGFBP7 contains 1 Ig-like C2-type (immunoglobulin-like) domain, 1 IGFBP N-terminal domain and 1 Kazal-like domain. It binds IGF-I and IGF-II with a relatively low affinity. IGFBP7 stimulates prostacyclin (PGI2) production.
Alias Symbols: FSTL2, IGFBP-7, IGFBP-7v, MAC25, PSF, AGM, TAF, IBP-7, RAMSVPS, IGFBPRP1
Protein Interaction Partner: RBBP8, HNF1A, RTN4, DSTN, UBC, CHMP3, CCL21, VEGFA, CCL5, SDC1, INS, IGF2, IGF1, CXCL10, INHBA,
Protein Size: 282

Molecular Weight: 29 kDa

Gene ID: 3490

NCBI Accession: NM_001553, NP_001544

UniProt: Q16270

Pathways: Growth Factor Binding