NCKAP1L antibody (C-Term)

Catalog No. ABIN2773901

Product Details anti-NCKAP1L Antibody

Target: NCKAP1L (NCK-Associated Protein 1-Like (NCKAP1L))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Cow, Dog, Rat, Rabbit, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCKAP1L antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LPLLATDPSS FYSIEKDGYN NNIHCLTKAI IQVSAALFTL YNKNIETHLK

Predicted Reactivity: Cow: 85%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against NCKAP1L. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NCKAP1L

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1127 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NCKAP1L antibody (ABIN2773901)

Weiner, Marganski, Wu, Altschuler, Kirschner: "An actin-based wave generator organizes cell motility." in: PLoS biology, Vol. 5, Issue 9, pp. e221, (2007) (PubMed).

Target Details for NCKAP1L

Target: NCKAP1L (NCK-Associated Protein 1-Like (NCKAP1L))

Alternative Name: NCKAP1L (NCKAP1L Products)

Synonyms: HEM1 antibody, 4930568P13Rik antibody, AI463083 antibody, Hem1 antibody, Hemp1 antibody, NCK associated protein 1 like antibody, zgc:172352 antibody, nck-associated protein 1-like antibody, NCK-associated protein 1-like antibody, NCKAP1L antibody, zgc:172352 antibody, LOC100030968 antibody, nckap1l antibody, LOC100618382 antibody, LOC100639088 antibody, Nckap1l antibody

Background: NCKAP1L is a member of the HEM family of tissue-specific transmembrane proteins which are highly conserved from invertebrates through mammals. This gene is only expressed in hematopoietic cells, while hematopoietic protein 2 is preferentially expressed in brain, heart, liver and testis. The function of the HEM1 product has not been established but it is thought to play an essential role in oogenesis.The protein encoded by this gene is a member of the HEM family of tissue-specific transmembrane proteins which are highly conserved from invertebrates through mammals. This gene is only expressed in hematopoietic cells, while hematopoietic protein 2 is preferentially expressed in brain, heart, liver and testis. The function of the HEM1 product has not been established but it is thought to play an essential role in oogenesis.
Alias Symbols: HEM1
Protein Interaction Partner: UBC, PRPF40A, GAS7, NOTCH1,
Protein Size: 1127

Molecular Weight: 128 kDa

Gene ID: 3071

NCBI Accession: NM_005337, NP_005328

UniProt: P55160

Pathways: Regulation of Actin Filament Polymerization