ICMT antibody (Middle Region)
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- Target See all ICMT Antibodies
- ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Horse, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ICMT antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GSNFNHVVQN EKSDTHTLVT SGVYAWFRHP SYVGWFYWSI GTQVMLCNPI
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%
- Characteristics
- This is a rabbit polyclonal antibody against ICMT. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ICMT
- Top Product
- Discover our top product ICMT Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 284 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Is there a preferred gestational age threshold of viability?: a survey of maternal-fetal medicine providers." in: The journal of maternal-fetal & neonatal medicine, Vol. 20, Issue 4, pp. 293-7, (2007) (PubMed).
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Is there a preferred gestational age threshold of viability?: a survey of maternal-fetal medicine providers." in: The journal of maternal-fetal & neonatal medicine, Vol. 20, Issue 4, pp. 293-7, (2007) (PubMed).
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- Target
- ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))
- Alternative Name
- ICMT (ICMT Products)
- Background
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ICMT is the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.
Alias Symbols: HSTE14, MGC39955, MST098, MSTP098, PCCMT, PCMT, PPMT
Protein Interaction Partner: ELAVL1, UBC, RAC2, RAC1, HRAS, RHOA,
Protein Size: 284 - Molecular Weight
- 32 kDa
- Gene ID
- 23463
- NCBI Accession
- NM_012405, NP_036537
- UniProt
- O60725
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