ACTR2 antibody (N-Term)

Catalog No. ABIN2773871

Product Details anti-ACTR2 Antibody

Target: ACTR2 (Actin-Related Protein 2 (ACTR2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACTR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: NGIVRNWDDM KHLWDYTFGP EKLNIDTRNC KILLTEPPMN PTKNREKIVE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ACTR2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACTR2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 399 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ACTR2

Target: ACTR2 (Actin-Related Protein 2 (ACTR2))

Alternative Name: ACTR2 (ACTR2 Products)

Background: ACTR2 is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion.The specific function of this gene has not yet been determined, however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ARP2
Protein Interaction Partner: UBC, SUMO2, SURF2, SRP9, SH3GL1, RPA1, RANGAP1, PRKACB, METTL1, DHPS, CALU, CALR, BAG1, ALAD, TPD52L2, TP53RK, GRPEL1, EFTUD1, P3H1, NIF3L1, RPRD1B, OSGEP, PANK4, RPRD1A, NSUN2, UFM1, PPME1, SH3GLB1, TPRKB, EEF2K, KIAA1279, HSPBP1, TTLL12, WDR4, ANP32B, C
Protein Size: 399

Molecular Weight: 45 kDa

Gene ID: 10097

NCBI Accession: NM_001005386, NP_001005386

UniProt: P61160

Pathways: RTK Signaling, Regulation of Actin Filament Polymerization