SP1 antibody (Middle Region)
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- Target See all SP1 Antibodies
- SP1 (Sp1 Transcription Factor (SP1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Goat, Pig, Rabbit, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SP1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TLTPIASAAS IPAGTVTVNA AQLSSMPGLQ TINLSALGTS GIQVHPIQGL
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 87%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against SP1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SP1
- Top Product
- Discover our top product SP1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 785 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SP1 (Sp1 Transcription Factor (SP1))
- Alternative Name
- SP1 (SP1 Products)
- Background
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SP1 belongs to the Sp1 C2H2-type zinc-finger protein family. It contains 3 C2H2-type zinc fingers. SP1 binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. It can interact with G/C-rich motifs from serotonin receptor promoter.
Alias Symbols: -
Protein Interaction Partner: JUN, UBC, HIC1, HDAC1, SP3, TP53, CTNNB1, ARHGAP21, SENP6, C3orf17, USP39, FOXM1, ESR1, DDX5, KIF1A, PPIG, TPI1, TFAP2A, NAP1L1, HDAC2, NUP62, MYC, HIF1A, POU2F1, SMAD3, DDX3X, TBP, SP1, RBL1, Taf4, tat, ESR2, VHL, YY1, CASP7, CASP6, CASP3, HTT, BRCA1, MA
Protein Size: 785 - Molecular Weight
- 81 kDa
- Gene ID
- 6667
- NCBI Accession
- NM_138473, NP_612482
- UniProt
- P08047
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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