MFRP antibody (Middle Region)

Catalog No. ABIN2773781

Product Details anti-MFRP Antibody

Target: MFRP (Membrane Frizzled-Related Protein (MFRP))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Rabbit, Cow, Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MFRP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HAIQLKIEAL SIESVASCLF DRLELSPEPE GPLLRVCGRV PPPTLNTNAS

Predicted Reactivity: Cow: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Pig: 93%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against MFRP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MFRP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 579 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MFRP antibody (ABIN2773781)

Sundin, Dharmaraj, Bhutto, Hasegawa, McLeod, Merges, Silval, Maumenee, Lutty: "Developmental basis of nanophthalmos: MFRP Is required for both prenatal ocular growth and postnatal emmetropization." in: Ophthalmic genetics, Vol. 29, Issue 1, pp. 1-9, (2008) (PubMed).

Target Details for MFRP

Target: MFRP (Membrane Frizzled-Related Protein (MFRP))

Alternative Name: MFRP (MFRP Products)

Synonyms: MFRP antibody, MCOP5 antibody, NNO2 antibody, RD6 antibody, rd6 antibody, C1q and TNF related 5 antibody, membrane frizzled-related protein antibody, C1QTNF5 antibody, MFRP antibody, Mfrp antibody

Background: MFRP is a member of the frizzled-related proteins. It may play a role in eye development, as mutations in this gene have been associated with nanophthalmos, posterior microphthalmia, retinitis pigmentosa, foveoschisis, and optic disc drusen. The protein is encoded by a bicistronic mRNA, which also encodes C1q and tumor necrosis factor related protein 5.
Alias Symbols: FLJ30570, NNO2, rd6, RD6, MCOP5
Protein Interaction Partner: UBC, C1QTNF5,
Protein Size: 579

Molecular Weight: 62 kDa

Gene ID: 83552

NCBI Accession: NM_031433, NP_113621

UniProt: Q9BY79